Search CLASH, Gene Expression, or microRNA Expression

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Step 3: Select cell line or tissue:

Step 4: Enter microRNA, target name, or gene ID(s):

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For multiple miRNAs, show targets found for every entered miRNA.

CLASHub v1.2 is an integrated platform for exploring microRNA-target interactions and multi-omics datasets.

The CLASHub Database supports exploration of microRNA-target interactions across four model organisms: Human, Mouse, Drosophila, and C. elegans. It currently hosts 146 CLASH datasets (55 published and 91 newly generated by our lab), together with 245 RNA-seq and 157 miRNA-seq datasets covering matched cell lines and tissues. CLASH (Crosslinking, Ligation, and Sequencing of Hybrids) directly captures miRNA-target pairs bound to AGO proteins, providing a more accurate view of regulation than prediction alone.

Beyond the database, CLASHub Analyzer provides built-in tools for fast, in-depth analysis, including CLASH data processing, miRNA-seq analysis, RNA-seq analysis, and cumulative fraction curve generation. These tools support precise identification of miRNA binding sites and quantitative assessment of miRNA impact on gene expression.

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Publication

Li L, Sheng P, Hiers NM, et al. CLASHub is an integrated database and analytical platform for microRNA-target interactions. Nature Communications. 2026. DOI: 10.1038/s41467-026-72902-x